HCP RESOURCES
Cologuard® resources for HCPs
You can download and share resources with your peers directly from this page, or you can contact a rep to request materials. If you have any questions or need further assistance, please call Customer Care at 1-844-870-8870 or chat online. You may also find answers to any questions on the FAQs page.
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Clinical information
The Cologuard Plus™ Test Clinician Brochure
Complete prescribing information for the Cologuard Plus test.
Study Data for the Cologuard Plus Test as Published in The New England Journal of Medicine
Study published in 2024 detailing the sensitivity, specificity, and other clinical data for the Cologuard Plus test.
Imperiale TF, Porter K, Zella J, et al. Next-generation multitarget stool DNA test for colorectal cancer screening. 2024.
The Cologuard Test Clinician Brochure
Complete prescribing information for the Cologuard test.
Pivotal Study Data for the Cologuard Test as Published in The New England Journal of Medicine
Pivotal study published in 2014 detailing the sensitivity, specificity, and other clinical data for the Cologuard test.
Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. 2014.
Retrospective Study Data on Cologuard Adherence as Published in the International Journal of Colorectal Disease
Retrospective study published in 2025 examining adherence rates among first time Cologuard users.
Le QA, Greene M, Gohil S, et al. Adherence to multi-target stool DNA testing for colorectal cancer screening in the United States. 2025.
Study Data on Colonoscopy Findings as Published in Cancer Prevention Research
Study published in 2022 examining how a positive FIT or mt-sDNA test influenced neoplasia detection during follow-up colonoscopy, compared to routine screening without a prior stool test.
Anderson JC, Robinson CM, Hisey W, Limburg PJ, Butterly LF. Colonoscopy findings in FIT+ and mt-sDNA+ patients versus in colonoscopy-only patients: New Hampshire Colonoscopy Registry Data. 2022.
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Operational information
After Visit Summary Letter
Send this letter to your patients after prescribing the Cologuard test to set expectations once they receive it.
Select Language:- English (US)
- English (US)
- Español (Spanish)
- العربية (Arabic)
- Français (French)
- Kreyòl Ayisyen (Haitian Creole)
- हिंदी (Hindi)
- 한국어 (Korean)
- 中文(繁體 ) Chinese (Traditional)
- Portuguese
- Русский (Russian)
- Tagalog/Filipino
- Tiếng Việt (Vietnamese)
Cologuard Rescreening Order Letter
Complete and send this letter to patients who received a negative Cologuard result 3+ years ago (overdue) and HCP has ordered another Cologuard test for the patient.
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Patient outreach letters
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GI resources
ACA=Affordable Care Act; CRC=colorectal cancer; EMR=electronic medical record; GI=gastrointestinal; HCP=healthcare provider.