HCP RESOURCES


Cologuard® resources for HCPs

You can download and share resources with your peers directly from this page, or you can contact a rep to request materials. If you have any questions or need further assistance, please call Customer Care at 1-844-870-8870 or chat online. You may also find answers to any questions on the FAQs page.

FILTERS

  • Clinical information

    The Cologuard Plus™ Test Clinician Brochure


    Complete prescribing information for the Cologuard Plus test.

    Study Data for the Cologuard Plus Test as Published in The New England Journal of Medicine


    Study published in 2024 detailing the sensitivity, specificity, and other clinical data for the Cologuard Plus test.


    Imperiale TF, Porter K, Zella J, et al. Next-generation multitarget stool DNA test for colorectal cancer screening. 2024.

    The Cologuard Test Clinician Brochure


    Complete prescribing information for the Cologuard test.

    Pivotal Study Data for the Cologuard Test as Published in The New England Journal of Medicine

    Pivotal study published in 2014 detailing the sensitivity, specificity, and other clinical data for the Cologuard test.

     

    Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. 2014.

    Retrospective Study Data on Cologuard Adherence as Published in the International Journal of Colorectal Disease


    Retrospective study published in 2025 examining adherence rates among first time Cologuard users.

     

    Le QA, Greene M, Gohil S, et al. Adherence to multi-target stool DNA testing for colorectal cancer screening in the United States. 2025.

    Study Data on Colonoscopy Findings as Published in Cancer Prevention Research


    Study published in 2022 examining how a positive FIT or mt-sDNA test influenced neoplasia detection during follow-up colonoscopy, compared to routine screening without a prior stool test.

     

    Anderson JC, Robinson CM, Hisey W, Limburg PJ, Butterly LF. Colonoscopy findings in FIT+ and mt-sDNA+ patients versus in colonoscopy-only patients: New Hampshire Colonoscopy Registry Data. 2022.

  • Operational information

    After Visit Summary Letter


    Send this letter to your patients after prescribing the Cologuard test to set expectations once they receive it.

    Select Language:
    • English (US)
    • English (US)
    • Español (Spanish)
    • العربية (Arabic)
    • Français (French)
    • Kreyòl Ayisyen (Haitian Creole)
    • हिंदी (Hindi)
    • 한국어 (Korean)
    • 中文(繁體 ) Chinese (Traditional)
    • Portuguese
    • Русский (Russian)
    • Tagalog/Filipino
    • Tiếng Việt (Vietnamese)
    English (US)
    Español (Spanish)
    العربية (Arabic)
    Français (French)
    Kreyòl Ayisyen (Haitian Creole)
    हिंदी (Hindi)
    한국어 (Korean)
    中文(繁體 ) Chinese (Traditional)
    Русский (Russian)
    Tagalog/Filipino
    Tiếng Việt (Vietnamese)

    Patients Aged 45-49 Years Screening Letter


    Complete and send this letter template to eligible patients aged 45-49 years. It describes how CRC affects this age group and how the Cologuard test may be an appropriate option.

    Patient Screening Letter


    Complete and send this letter template to eligible patients in your practice who are due for CRC screening. It describes how a noninvasive test may be an appropriate option.

    Patient Order Letter


    Complete and send this letter template to eligible patients in your practice for whom you have ordered a Cologuard test to ensure they are clear on the screening process.

    Cologuard Rescreening Letter


    Complete and send this letter template to your patients who are due for rescreening and are eligible for a Cologuard test.

    Cologuard Rescreening Order Letter


    Complete and send this letter to patients who received a negative Cologuard result 3+ years ago (overdue) and HCP has ordered another Cologuard test for the patient.

    Cologuard Rescreening Advance Order Letter


    Complete and send this letter to patients who received a negative Cologuard result less than 3 years ago (due soon) and HCP has ordered another Cologuard test for the patient. It will ship when they are eligible to be screened.

    Letter of Medical Necessity


    Complete and send this letter template to your patient’s insurance company if you deem the Cologuard test to be medically necessary for your eligible patient.

    Unreturned Kit Reminder Letter


    A letter that you can customize and send to patients who have not completed screening with the Cologuard test. It reinforces the importance of CRC screening and ensures that patients are clear on next steps. 

  • Patient outreach letters 

  • GI resources



ACA=Affordable Care Act; CRC=colorectal cancer; EMR=electronic medical record; GI=gastrointestinal; HCP=healthcare provider.