COVERAGE

The same easy ordering and broad Cologuard® coverage1

Flow chart showing how Exact Sciences will determine which Cologuard® test is covered by a patient’s insurance.
The Cologuard Plus test is coming soon.

Eligible patients will get the latest test covered by their insurance to ensure uninterrupted access.


Keep ordering Cologuard the same way you always have, and Exact Sciences will determine which test is covered by a patient’s insurance and send them the latest test that is appropriately reimbursed. This way, there are no disruptions in coverage and you can focus on getting your patients screened for colorectal cancer (CRC).

As the Cologuard Plus™ test is available for a longer period, access will expand.


Check in for updates as the Cologuard Plus test becomes available to more patient populations. In the meantime, enroll in the Provider Status Report for biweekly updates on your Cologuard orders, including which patients received the Cologuard Plus test. Sign up for single or multiple locations.


The Cologuard Plus test is available for eligible patients insured by:

  • Medicare Part B

This list is updated periodically and may not include every insurer. Check back for updates. Exceptions for coverage may apply; only your patients' insurers can confirm how the Cologuard Plus test would be covered.

Most insured patients pay $0 for Cologuard1*

The Cologuard test is covered by Medicare and Medicare Advantage with no co-pay or deductible for eligible patients.2,3

> 96%

Nationwide, over 96% of all Cologuard patients 45+ have no out-of-pocket costs for screening1*

Insurance coverage

Eligible patients who are actively enrolled in any state Medicaid program can access the Cologuard test. No payment will be expected from the patient unless the plan requires a co-pay.2†

Follow-up colonoscopy coverage

There is no cost sharing for colonoscopy following a positive Cologuard result2,4

January 2022

The federal government issued guidance making it clear that a colonoscopy after a positive noninvasive CRC screening test should be considered part of the screening process.2,4‡

2023 Policy Changes

Positive results from a noninvasive stool-based test, including the Cologuard test, qualify for coverage of follow-up colonoscopy with no cost sharing.2,4‡

As of 2023, Affordable Care Act (ACA) and Centers for Medicare & Medicaid Services (CMS) guidance requires coverage to encourage CRC screening by reducing financial barriers.2,4

Follow-up Colonoscopy Summary Guide

This guide for Providers and Medical Offices, from the American Gastroenterological Association and Fight CRC, provides more information about this regulatory change, what it means for providers, and how to code the change correctly.

optimize your experience
Which colorectal cancer (CRC) screening option do you prescribe most often to your average-risk patients?
Your most prescribed CRC screening option:
Doctor sitting with an eligible patient in their office and comforting her.

Exact Sciences is committed to helping eligible patients access and afford CRC screening

Insurance support:

  • Verification of benefits, as requested
  • Patient-assisted insurance appeals

Financial support programs:

  • Flexible payment plans
  • Financial assistance program, based on eligibility

Customer Care:


Find a specific insurer to see if the Cologuard test is covered for your eligible patients



  • * Exact Sciences estimate based on historical patient billing as of November 2024. Exceptions for coverage may apply; only your patients’ insurers can confirm how the Cologuard test would be covered.1
  • The Cologuard test is a preventive service for NY Medicaid and members have no financial responsibility.2
  • For patients with traditional Medicare, a colonoscopy after a positive Cologuard result is still a screening colonoscopy based on updated Centers for Medicare & Medicaid Services regulations, effective January 1, 2023. Medicare does not apply cost sharing to screening colonoscopy. This update does not apply to commercial plans with exempted status.2,4