Regular colorectal cancer (CRC) screening may help
reduce mortality rates and has the potential to save lives
1

The US Preventive Services Task Force (USPSTF) and the American Cancer Society (ACS) both recommend screening patients at average risk for CRC starting at age 45.1,2

(Grade B recommendation)1*

Of the ~60 million average-risk patients aged 45 and older eligible for CRC screening3,4‡:
~19 Million
Screening-eligible patients are aged 45 to 49 years5

Despite the American Cancer Society (ACS) lowering its initial screening age to 45 in 20182:

people
Only 1 in 5 patients aged 45 to 49 years recently reported screening for CRC4
Initiating CRC screening at age 45 provides multiple benefits according to projection models, including averted CRC cases, a reduction in CRC-related deaths, and an increase in patient life-years gained.1
  • Incidence and severity in patients <50

    CRC incidence in younger populations is estimated to increase by 90% by 2030

    Among patients younger than 50 years:

    51%
    Increase in the incidence
    of CRC since 19942
    52%
    Were diagnosed with more
    advanced stages of CRC vs
    40% of patients aged 50+ years
    (2004-2015)7||

    §Younger population is defined by the 20 to 34 year age group.6

There is significant risk in waiting to screen for CRC8

0
Symptoms
Many patients with early-stage CRC
have no symptoms, making proactive
screening the only way to detect CRC9
91%
Survival Rate
The 5-year relative survival rate
(stages I and II)|| is 91%, but when
diagnosed in stage IV, that number
drops to 14%8

5-year survival rates by stage of CRC8,10¶:

91%
Stages I, IIa, IIb (Localized)
73%
Stages IIc, III (Regional)
14%
Stage IV (Distant)

Unfortunately, more than half of patients are diagnosed with regional or distant disease.8#

Financial impact

For each patient
diagnosed in stage I or II

$57,901

is the average cost of first-year
CRC treatment11**††
For each patient
diagnosed in stage IV

$108,599

is the average cost of first-year
CRC treatment11††

All cost estimates adjusted to 2013 dollars.