Cologuard is a noninvasive colorectal cancer (CRC) screening that can help address potential barriers for patients

  • Cologuard is shipped directly to patients' homes upon ordering.

    Accompanied by 2 months of personalized outreach to facilitate screening completion, including a welcome call as well as mail, email, or text message reminders.

    Cologuard kit

    The Cologuard Collection Kit

    The Cologuard collection kit is designed for ease of use at home. If a patient has questions, a customer support specialist is available to assist via phone at 1-844-870-8870.

     

  • Cologuard can be completed in the comfort of home and does not require special preparation, dietary or medication changes, sedation, or time off from work.

    • Patients should plan to collect their sample when they can get it back to UPS that same day or the next day
    • Patients should add a reminder to their calendars or phones for the day they will collect their sample

    The Customer Care Center is available 24/7 to help patients complete their Cologuard collection kit at 1-844-870-8870 and via chat.

    How-to-use
    video

    How to use Cologuard

    See how patients can screen for CRC at home with Cologuard.

    Choose your desired language for the video below to see how easy Cologuard can be to use
    • English (US)
    • English (US)
    • العربية (Arabic)
    • 简体中文 (Simplified Chinese)
    • Français (French)
    • 한국어 (Korean)
    • Русский (Russian)
    • Español (Spanish)
    • Tagalog/Filipino
    • Tiếng Việt (Vietnamese)

  • Patients can choose the no-cost return option that works best for them. They may:

    • Request a contact-free UPS® pickup: Call 1-844-870-8870 for help or visit Cologuard.com/UPS to schedule it on their own
    • Drop it off at UPS: Visit Cologuard.com/UPS to see local options and hours. Remember, some locations are closed on Sundays or holidays.

    Healthcare providers usually receive the test results within 2 weeks.

    Define results

    What do the results mean?

    A positive result does not necessarily mean the patient has CRC. It means that Cologuard detected altered DNA and/or hemoglobin in the patient's stool. Patients with a positive result should have a colonoscopy.1

    A negative result means that Cologuard did not detect altered DNA and/or hemoglobin in the stool. Patients with a negative result should continue in an appropriate screening program.1 The American Cancer Society recommends that patients get screened for CRC again 3 years after a negative Cologuard result.2

    Sample Could Not Be Processed (SCNBP) means that the sample received by the lab could not be processed for reasons such as: required labeling information was missing, buffer addition could not be verified, stool sample exceeds allowable weight, collection kit was damaged, an empty kit was received. For these, the patient will be contacted by Exact Sciences and a fax will be sent to the provider.

    No Result Obtained (NRO) means that a valid Cologuard result was not obtained for reasons such as: insufficient DNA volume, fecal hemoglobin sample did not produce a valid result, technical issues, etc. For these, the patient will be contacted by Exact Sciences and a fax will be sent to the provider.

    Reminder: Test results are provided to HCPs to communicate results
    with patients; results will only be delivered directly to the patient if specifically requested.

    False positives and false negatives do occur. In a clinical study, 13% of patients without colorectal cancer or advanced adenomas received a positive result (false positive) and 8% of patients with cancer received a negative result (false negative). Cologuard performance when used for repeat testing has not been evaluated or established.

3 Tips for Cologuard collection kit completion

  • Reinforce the importance of screening on time

    • Explain how screening on time is important because when detected in early stages, CRC is more treatable3*†

  • Set expectations

    • Set a 2-week timeframe to use the Cologuard collection kit
    • Expect welcome outreach from the Exact Sciences Customer Care Center

  • Confirm collection and return process

    • Store the Cologuard collection kit on the back of the toilet for easy use
    • An acceptable stool sample should be no larger than the bottle of liquid in the kit and should not be provided if there is diarrhea or blood in the stool
    • Patients should plan to collect their sample when they can get it back to UPS® on that same day or the next day

    The Customer Care Center is available 24/7 to help patients complete their Cologuard collection kit at 1-844-870-8870 and via chat

Ordering Cologuard via telehealth

Your patients can learn more about telehealth and, if they wish, also connect with a third-party telehealth provider at the Cologuard patient website, as a way to determine if Cologuard is right for them.
See which patients are appropriate for Cologuard
*

Based on people diagnosed with CRC in stage I, stage IIa, or stage IIb between 2010 and 2016.4,5

†

Per American Joint Committee on Cancer's (AJCC) staging system: Localized = Stage I, IIa, IIb. Regional = stage IIc and III. Distant = stage IV.5

References: 1. Wolf AMD, Fontham ETH, Church TR, et al. Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA Cancer J Clin. 2018;68(4):250-281. 2. Cologuard® Clinician Brochure. Madison, WI: Exact Sciences Corporation. 3. SEER cancer statistics review (CSR) 1975-2016: Table 6.10 incidence and mortality rates by age. NIH National Cancer Institute: Surveillance, Epidemiology, and End Results Program (SEER). Accessed November 29, 2022. https://seer.cancer.gov/csr/1975_2016/browse_csr.php?sectionSEL=6&pageSEL=sect_06_table.10. 4. Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2022. CA Cancer J Clin. 2022;72(1):7-33. 5. Survival rates for colorectal cancer. American Cancer Society. Accessed November 29, 2022. https://www.cancer.org/cancer/colon-rectal-cancer/detection-diagnosis-staging/survival-rates.html.