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Adherence to the Cologuard test is 71% for the first screening, and it grows to 83% and 94% for the second and third screening, respectively, as established by real-world data.1,2*

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Correct answer: True

For the first screening with the Cologuard test, adherence is 71%.1 As reported in real-world data, the adherence rate for the second screening 3 years later rises to 83%; and continues to increase to 94% for the third screening.2*

References and footnotes

  • *Based on a retrospective cohort study of 481,748 patients aged 45-75 who received a Cologuard kit between January 1 and December 31, 2023, and who had received a negative Cologuard result at least 2.5 years ago.2
  • 1.Le Q, Greene M, Ozbay AB, Dore M, Fendrick AM, Limburg P. Cross-sectional adherence with the multi-target stool DNA test for colorectal cancer screening among four largest payors in the country. Abstract presented at: American College of Gastroenterology (ACG) 2024; October 25-30, 2024; Philadelphia, PA.
  • 2.Greene M, Dore M, Ebner DW, et al. Real-world multi-target stool DNA longitudinal adherence for colorectal cancer re-screening in a large, national population. J Clin Oncol. 2024;42(16):e15633.