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Correct answer: 51%

CRC incidence has increased 51% in the past 30 years in adults under 50.1 The United States Preventive Services Task Force and American Cancer Society both recommend starting CRC screening as soon as an average-risk patient turns 45, partly because of this rising incidence.1,2*†

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Correct answer: 51%

In the past 30 years, there has been a 51% increase in CRC incidence in adults under the age of 50.1 This rising incidence contributes to the United States Preventive Services Task Force and American Cancer Society recommendation to start screening at 45 years old.*†1,2

References and footnotes

  • *The ACS makes a qualified recommendation for screening in eligible patients aged 45 to 49 years, indicating clear evidence of benefit of screening but less certainty about the balance of benefits, harms, and patient preferences. ACS-recommended screening modalities include high-sensitivity stool-based tests or structural (visual) examinations.1
  • †The USPSTF found adequate evidence that screening eligible patients aged 45 to 49 years provides a moderate benefit in reducing CRC deaths and increasing life-years gained. USPSTF-recommended screening modalities include stool-based tests or direct visualization tests.2
  • 1.Wolf AMD, Fontham ETH, Church TR, et al. Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA Cancer J Clin. 2018;68(4):250-281.
  • 2.Davidson KW, Barry MJ, Mangione CM, et al. Screening for colorectal cancer: US Preventive Services Task Force recommendation statement. JAMA. 2021;325(19):1965-1977.